The experience of chemotherapy for mesothelioma pulmonary cancer potential promising show

Treatment with a Japanese real estate experience known chemotherapy for the treatment of different cancerous tumours, they were together a promising to conventional treatment alternative or standard published Advanced Lung, according to the American Cancer Research, cancer case the result of the experience patrol "clinical cancer Research."

The clinical trial was conducted in several centres and in the second phase of experience involved 56 patients with advanced commonly lung cancer cases.

The results of the experience of using real estate and Irenotikan S - 1 in terms of level of response and the aggravation continues life without cancer patients and the total length of stay, similar or better results for the treatment of the standard chemotherapy regime Platini.

Platinum toxic treatment

Because they are simple experience, with all participants received the same experimental, treatment without deal with standard chemotherapy treatment group, researchers could not directly compare the two methods of treatment benefits.

However, they do not mention if experimental treatment side effects less serious than those usually caused the standard treatment. It seems that patients and their doctors rejecting the toxicity of chemotherapy, the standard deck, the absence of usefulness in the lives of patients, which reinforces the need for effective treatment, less toxic effects.

The study author and Professor of Oncology, Faculty of medicine, University of Osaka created kinky Isamu Okamoto, Japan should perform a repair "double track" for a direct comparison between the experimental treatment and to establish standard treatment of benefits extend the survival of patients with the use of real estate and Irenotikan S-1.

Three mechanisms of action

S-1 drugs approved its use in Japan and Korea, which has shown significant benefit in the treatment of cancer of the digestive tract, but it's still in clinical trials in other countries, such as Europe and the United States.

This available in the form of capsules real complex, three different mechanisms. Dissolve in one to Vrurassel (5 - FU), as soon as his body. Chemotherapy Alvrurassel and other drugs often used to treat cancer of the colon and rectum.

There is a second part of the drug S - 1 will continue in the fixed Vrurassel production, while the third is designed to deal with the effects of toxic Vrurassel, Kalgthian and vomiting.

Irenotikan drugs is injected intravenously and was originally developed and tested in Japan, the United States has been approved in 1994 and is often used to treat cancer of the colon. And is currently used in Japan to treat cancer of the lung, but used in other countries.

Level of intervention and survival

Japanese researchers believe that the combination of real estate and S - 1 provides Irenotikan impact of solidarity. S-1 as the first treatment chemotherapy for advanced lung cancer cases drug tests response level was 22 %, while continuing to remain at an average 10.2 months.

For the completion of the study, registered in this patient trial with advanced lung cancer cases did not receive any treatment in 14 treatment centres in Japan, where they received an average of five experimental treatment sessions. The level of response was 28 % and the average stay on the five months cancer aggravation and overall survival average of 15 months.

Okamoto believes that these positive results compared levels of response two-way Platinum chemotherapy treatment test results will vary between 17 and 33 % and survival periods range from the aggravation of the cases of cancer between three and five months and average total stay of 7 to 14 months.

The researcher, this promising experimental treatment alternative, but needs more random test during both directions.Next Page>>